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1.

A critical role for altered red cell cation permeability in pathogenesis of sickle cell disease and other haemolytic anaemias.

Gibson, John S; Stewart, Gordon W.

Br J Haematol ; 202(3): 462-464, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37096935

2.

The cation-leaky hereditary stomatocytosis syndromes: A tale of six proteins.

Stewart, Gordon W; Gibson, John S; Rees, David C.

Br J Haematol ; 203(4): 509-522, 2023 11.

Artigo em Inglês | MEDLINE | ID: mdl-37679660

3.

Males with sickle cell disease have higher risks of cerebrovascular disease, increased inflammation, and a reduced response to hydroxyurea.

Di Mauro, Margherita; El Hoss, Sara; Nardo-Marino, Amina; Stuart-Smith, Sara; Strouboulis, John; Gibson, John S; Rees, David C; Brewin, John N.

Am J Hematol ; 98(11): E341-E344, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37646569

4.

The pleiotropic effects of α-thalassemia on HbSS and HbSC sickle cell disease: Reduced erythrocyte cation co-transport activity, serum erythropoietin, and transfusion burden, do not translate into increased survival.

Brewin, John N; Nardo-Marino, Amina; Stuart-Smith, Sara; El Hoss, Sara; Hanneman, Anke; Strouboulis, John; Menzel, Stephan; Gibson, John S; Rees, David C.

Am J Hematol ; 97(10): 1275-1285, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35802781

5.

Regulation of erythrocyte Na⁺/K⁺/2Cl^- cotransport by an oxygen-switched kinase cascade.

Zheng, Suilan; Krump, Nathan A; McKenna, Mary M; Li, Yen-Hsing; Hannemann, Anke; Garrett, Lisa J; Gibson, John S; Bodine, David M; Low, Philip S.

J Biol Chem ; 294(7): 2519-2528, 2019 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-30563844

6.

The role of WNK in modulation of KCl cotransport activity in red cells from normal individuals and patients with sickle cell anaemia.

Lu, David C-Y; Hannemann, Anke; Wadud, Rasiqh; Rees, David C; Brewin, John N; Low, Philip S; Gibson, John S.

Pflugers Arch ; 471(11-12): 1539-1549, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31729557

7.

Oxidative stress and phosphatidylserine exposure in red cells from patients with sickle cell anaemia.

Hannemann, Anke; Rees, David C; Brewin, John N; Noe, Andreas; Low, Ben; Gibson, John S.

Br J Haematol ; 182(4): 567-578, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29938778

8.

The super sickling haemoglobin HbS-Oman: a study of red cell sickling, K⁺ permeability and associations with disease severity in patients heterozygous for HbA and HbS-Oman (HbA/S-Oman genotype).

Al Balushi, Halima W M; Wali, Yasser; Al Awadi, Maha; Al-Subhi, Taimoora; Rees, David C; Brewin, John N; Hannemann, Anke; Gibson, John S.

Br J Haematol ; 179(2): 256-265, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28699687

9.

A novel mechanism for pathogenesis of sickle cell disease with therapeutic implications: Band 3 tyrosine phosphorylation.

Gibson, John S.

Br J Haematol ; 190(4): 488-489, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32394428

10.

Lipid metabolism in terminal erythropoiesis.

Gibson, John S; Rees, David C.

Blood ; 131(26): 2872-2874, 2018 06 28.

Artigo em Inglês | MEDLINE | ID: mdl-29954819

11.

The clinical significance of K-Cl cotransport activity in red cells of patients with HbSC disease.

Rees, David C; Thein, Swee Lay; Osei, Anna; Drasar, Emma; Tewari, Sanjay; Hannemann, Anke; Gibson, John S.

Haematologica ; 100(5): 595-600, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25749827

12.

Effects of 5-hydroxymethyl-2-furfural on the volume and membrane permeability of red blood cells from patients with sickle cell disease.

Hannemann, Anke; Cytlak, Urszula M; Rees, David C; Tewari, Sanjay; Gibson, John S.

J Physiol ; 592(18): 4039-49, 2014 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-25015917

13.

Mechanism of O2-sensitive red cell properties.

Gibson, John S.

Blood ; 128(23): 2593-2595, 2016 12 08.

Artigo em Inglês | MEDLINE | ID: mdl-27932326

14.

Emerging drug targets for sickle cell disease: shedding light on new knowledge and advances at the molecular level.

Gibson, John S; Rees, David C.

Expert Opin Ther Targets ; 27(2): 133-149, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36803179

15.

Biomarkers in sickle cell disease.

Rees, David C; Gibson, John S.

Br J Haematol ; 156(4): 433-45, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22122125

16.

Does Plasma Inhibit the Activity of KCl Cotransport in Red Cells From LK Sheep?

Lu, David C-Y; Hannemann, Anke; Gibson, John S.

Front Physiol ; 13: 904280, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35685289

17.

Nocturnal enuresis and K+ transport in red blood cells from patients with sickle cell anemia.

Tewari, Sanjay; Rees, David C; Hannemann, Anke; Gbotosho, Oluwabukola T; Al Balushi, Halima W M; Gibson, John S.

Haematologica ; 101(12): e469-e472, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27587381

18.

Rapid effects of hypoxia on H+ homeostasis in articular chondrocytes.

Gibson, John S; McCartney, David; Sumpter, Joanna; Fairfax, Thomas P A; Milner, Peter I; Edwards, Hannah L; Wilkins, Robert J.

Pflugers Arch ; 458(6): 1085-92, 2009 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-19629519

19.

The effect of the antisickling compound GBT1118 on the permeability of red blood cells from patients with sickle cell anemia.

Al Balushi, Halima; Dufu, Kobina; Rees, David C; Brewin, John N; Hannemann, Anke; Oksenberg, Donna; Lu, David C-Y; Gibson, John S.

Physiol Rep ; 7(6): e14027, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30916477

20.

The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia.

Al Balushi, Halima W M; Rees, David C; Brewin, John N; Hannemann, Anke; Gibson, John S.

Physiol Rep ; 6(5)2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29504282

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